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Article from Source:Cancer letters 2014 Aug 28; 351(1): 13-22 from Library Catalog Search: peptides AND cancer cells

Peptide-based cancer therapy: opportunity and challenge.

Front cover image for Peptide-based cancer therapy: opportunity and challenge.
Peptide-based cancer therapy: opportunity and challenge.
Format:
Article
Publication year:
2014
 
|
Peer-reviewed
Source:
  • Cancer letters 2014 Aug 28; 351(1): 13-22
Held by:
Saint Leo University Cannon Memorial Library
 
 
ISSN:
  • 0304-3835
DOI:
 
Subjects:
Summary:
  • Cancer is one of the leading causes of death worldwide. Conventional cancer therapies mainly focus on mass cell killing without high specificity and often cause severe side effects and toxicities. Peptides are a novel class of anticancer agents that could specifically target cancer cells with lower toxicity to normal tissues, which will offer new opportunities for cancer prevention and treatment. Anticancer peptides face several therapeutic challenges. In this review, we present the sources and mechanisms of anticancer peptides and further discuss modification strategies to improve the anticancer effects of bioactive peptides.
Database:
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.